As biopharmaceutical pipelines grow more complex, downstream purification demands systems that can evolve alongside the process. From early-stage development to full GMP commercial manufacturing, flexibility, control, and scalability are critical to success.
FlexiPro™ Chrom from VERDOT is a next-generation single-use chromatography system engineered to support the entire bioprocess lifecycle. With a compact footprint, precise process control, and exceptional sensitivity, FlexiPro™ Chrom delivers high-performance chromatography across multiple process scales without compromise.
Start Small, Think Big
FlexiPro™ Chrom is designed to grow with your process, allowing seamless transition from R&D and process development to GMP manufacturing. Its scalable architecture enables consistent chromatography performance across multiple production stages, minimizing process changes and reducing risk during scale-up.
This “start small, think big” approach supports:
- Faster process development
- Predictable scalability
- Simplified technology transfer
Four Skids in One, One Scalable Platform
FlexiPro™ Chrom delivers unmatched scalability with a true “four skids in one” design. Using interchangeable single-use flow kits, you can scale from 10 mL/min to 10 L/min in less than 15 minutes—without changing systems.
10 mL/min → 10 L/min
One system. Four flow ranges. < 15 minutes to scale.
FlexiPro™ Chrom Flow Kit Overview
| Flow Kit | Flow Range (LPH) | Typical Stage |
|---|---|---|
| ULFK | 0.6 – 6.6 | R&D & method development |
| VLFK | 1 – 30 | Process optimization |
| LFK | 5 – 150 | Pilot & scale-up |
| HFK | 20 – 560 | GMP & commercial manufacturing |
Why This Matters
- Replace multiple chromatography skids with one system
- Maintain consistent control from development through GMP
- Reduce footprint, capital cost, and validation complexity
- Adapt instantly as process demands change
FlexiPro™ Chrom is built to evolve with your pipeline—delivering flexibility today and confidence at commercial scale.
Compact Footprint, Big Performance
Space is often at a premium in laboratories and manufacturing facilities. FlexiPro™ Chrom’s compact design maximizes performance while minimizing footprint—making it ideal for both new facilities and retrofits.
Ultra-Low Hold-Up Volume for Maximum Yield
In downstream processing, every milliliter matters. FlexiPro™ Chrom is engineered with ultra-low hold-up volume, helping preserve valuable product and improve overall recovery.
This design feature is especially beneficial for:
- High-value biologics
- Early-stage development batches
- Processes requiring maximum yield and consistency
Unmatched Versatility for Modern Bioprocessing
Modern downstream workflows require adaptability. FlexiPro™ Chrom offers exceptional versatility, making it suitable for a wide range of chromatography applications and biomolecule types.
Key advantages include:
- Compatibility with multiple chromatography resins
- Support for diverse purification strategies
- Configurable system layouts to match process needs
This versatility allows manufacturers to respond quickly to changing production requirements without reinvesting in new hardware.
True Flexibility with Single-Use Design
FlexiPro™ Chrom’s single-use fluid path dramatically reduces operational complexity. By eliminating cleaning validation and lengthy changeovers, facilities gain greater flexibility and improved throughput.
Benefits of the single-use design include:
- Reduced downtime between batches
- Lower cross-contamination risk
- Faster product changeovers
- Simplified GMP compliance
Advanced Control for Reliable Results
Precise control is essential for reproducible chromatography performance. FlexiPro™ Chrom delivers accurate, real-time control of critical process parameters, ensuring consistent results from run to run.
Enhanced control capabilities support:
- Robust process optimization
- Improved batch-to-batch consistency
- Greater confidence during scale-up and GMP manufacturing
High Sensitivity for Process Insight
FlexiPro™ Chrom provides high sensitivity monitoring, enabling operators to detect subtle process changes and maintain tight control over purification performance.
This increased sensitivity helps:
- Identify deviations early
- Improve product quality
- Support data-driven decision-making
Intuitive Operation for Faster Adoption
Designed with usability in mind, FlexiPro™ Chrom features an intuitive interface that simplifies operation and reduces training time. This user-friendly design allows teams to focus on process optimization rather than system complexity.
How GMI Helps You Succeed with FlexiPro™ Chrom
As a trusted provider of advanced bioprocessing solutions, GMI supports FlexiPro™ Chrom systems from selection through implementation. Our team works closely with customers to ensure the system aligns with their process goals and regulatory requirements.
With GMI, you gain:
- Expert guidance on FlexiPro™ Chrom configuration
- Support for downstream process optimization
- Reliable service and long-term technical assistance
Elevate Your Downstream Process
FlexiPro™ Chrom delivers the flexibility, control, and performance today’s bioprocessing demands—without compromise.
Discover how FlexiPro™ Chrom can enhance your process: https://www.gmi-inc.com/wp-content/uploads/2025/12/Verdot-FlexiPro-Chrom-1080×1080-RGB-AW.pdf


