VERDOT InPlace™ and EasyPack™ Columns

Product Description

VERDOT Process-Scale LPLC Columns for GMP Manufacturing

Available in 200 mm to 2000 mm Inner Diameter

VERDOT’s InPlace™ and EasyPack™ Columns offer state-of-the-art process-scale Low Pressure Liquid Chromatography (LPLC) solutions designed for consistent, reproducible column packing using automated axial compression technology. This scalable technology ensures reliable performance from lab scale up to commercial manufacturing across column diameters from 20 cm to 200 cm.

Scalable Axial Compression Technology for Consistent Results

Axial compression packing directly translates from small to large scale, providing predictable and reproducible column performance. Simplified slurry transfer and bed consolidation protocols make first-time-right packing achievable at any scale.

Minimize Downtime, Maximize Confidence

Expert support is available for onsite column packing and troubleshooting to overcome unique procedural and environmental challenges. Innovative packing techniques ensure even the most challenging resins form stable, well-distributed beds for optimal chromatography.

Key Features of VERDOT Columns from GMI

• Flexible Size Range: Columns available from 200 mm to 2000 mm inner diameter, allowing confident scale-up.
• Automated Operation: Simplify packing and unpacking with VERDOT’s user-friendly control console supporting multiple column configurations.
• Optimized Flow Distribution: Specialized frit and flow distributor designs ensure uniform flow, even with difficult-to-pack resins.
• Compact & Lightweight: Up to 50% lighter and 17% shorter than comparable columns, optimizing space and handling.
• Efficient Repacking: Slurry sparging with air assistance reduces buffer use, enabling repacking in place within 1–4 hours.
• Easy Maintenance: Designed for straightforward cleaning, sanitization, and hoist-free maintenance with the VERDOT column lifter.
• Broad Resin Compatibility: Extensive technical resources cover packing for all commercial resins, including hard-to-pack and incompressible types.
• Onsite Support & Training: Dedicated service and training to minimize downtime and maximize user confidence.
• Regulatory Compliance: Comprehensive IQ/OQ and documentation packages to support regulatory submissions.

VERDOT columns, supported and serviced by GMI, provide the precision and reliability required for your GMP manufacturing processes. Contact us to learn how we can support your chromatography needs from installation through ongoing maintenance.