KLF Small Laboratory Fermenter
KLF Small Laboratory
Fermenter
The mobile Laboratory Fermenter NLF (total volumes from 16 to 30 litres)
can be easily integrated in a laboratory. Special features such as a double
jacketed vessel bottom for optimal temperature control and the double
mechanical seal with the removable stirrer shaft are standard equipment.
The KLF small laboratory
fermenter is the smallest unit in our CSTR series of bioreactors. Its design
permits straightforward interfacing with the Bioengineering modular
instrumentation and control system, so that more instruments and controls
can be added at any time (this is the first step in scaling up many
processes). A benchtop apparatus, the KLF is the only small laboratory
fermenter of its kind that can be sterilized in situ.
Flexibility, sturdy
construction and ease of operation make this small laboratory fermenter an
attractive choice in research and educational settings, especially for
scale-up and screening tasks. Its small volume helps hold down purchasing,
overhead and direct operating costs. The user need not rely on free
autoclave capacity, the fermenter does not have to be moved around, and
stirring can be continued during sterilization (particularly important for
sensitive media). What is more, the medium can be cooled down rapidly, and
the special port system allows sterile connection of the fermenter to
peripheral apparatus, even after sterilization.
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KLF Small Laboratory Fermenter
Design and Operation of the KLF Small Laboratory
Fermenter
Three interchangeable glass cylinders
with volumes from 2.4 to 3.7 L are available as fermenter vessels.
The stirrer can be driven from below or top through a mechanical
seal or with a magnetic coupling. A variety of impellers can be
attached to the shaft at any desired height, and changeovers for the
most diverse mixing strategies can be handled with ease. The
standard version features temperature control with an 800 heating
and cooling finger, stirrer speed control, and air metering with air
intake and exhaust filters. The Bioengineering modular
instrumentation and control system makes it possible to upgrade the
small laboratory fermenter to a fully equipped, computer-controlled
fermenter system. The following quantities can be measured and
controlled: pH, p02, redox potential, pCO2, turbidity, pressure,
torque, weight, level, and metering.
A range of options for culture media
mixing and gas dispersion permit the use of the small laboratory
fermenter for all kinds of aerobic and anaerobic cell cultures -
bacteria, yeasts, fungi, algae, plant and animal cells in suspension
- as well as micro carrier cultivations. The apparatus can be
adapted to work with explosive substances and at pressures up to 6
bar. Some sample applications:
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Straightforward batch
cultivation |
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Continuous cultivation monitored
by leveling tube or with weight, turbidity or level
measurement |
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Plant cell cultivation with
illuminator jacket and special stirring systems
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Cultivation of animal cell
cultures with special accessories including axial-flow and
radial-flow stirrers and aeration systems (ring and
sintered-metal spargers, bubble-free aerators)
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Unrestricted cultivation of
pathogens and genetically manipulated organisms in
compliance with all safety standards.
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You can reserve/order this instrument
by calling 763-712-8717 or by
completing the form on the Ordering Page.
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