Global Medical Instrumentation, Inc.
 
 
 
 
 









New Brunswick BioFlo 3000
Pilot Fermentor

 


NBS BioFlo 3000

BioFlo 3000 screen displays over 75 setpoints and variables. The vacuum fluorescent display provides easy access to every phase of the process,

 including 13 control loops that simplify start-up, cell growth and process manipulation.

NBS BioFlo 3000 Features:
  • Built-in Gas-Mixer Optimizes Dissolved Oxygen Levels For High-Density Culture. Two-Gas Mixing in Fermentation provides automatic or manual blending of supplemental oxygen and air. Create air, oxygen, and agitation control cascades that respond to oxygen-demanding microbes, while limiting foam and shear. Four-Gas Mixing in Cell Culture, blends air, oxygen, carbon dioxide, and nitrogen for precise and gentle automatic control of both pH and dissolved oxygen
  • 350 mM/L/Hr Oxygen Transfer Rate obtained through powerful fermentation agitation motors and 6-bladed Rushton impellers
  • Choice of 12 Interchangeable Vessels. Fermentation vessels offered with or without side ports, in four sizes from 1.6 through 14 liters. Glass-jacketed cell culture vessels, 2.2 through 14 liters total volume
  • Stainless-Steel Heat Exchanger forms the rounded bottom of fermentation vessel assemblies. Allows the shortest autoclave time, with no impeding double-insulating glass to slow sterilization. Large-area high-conductivity steel surface provides superior temperature uniformity and the most efficient heat-transfer characteristics. The best choice for fermentation, especially for high-density cultures and for temperature induction
  • Vessel Side Ports support chemostat operation
  • Optional Low Side Entry Ports (available in fermentor vessels only) - two 19 mm ports in the stainless-steel heat-exchanger support additional probes, which enter the vessel below the impeller. 12 mm adapter available
  • Integrated Vessel, Console, Controller and Pumps conserve bench space and simplify connections
  • Choice of Thermal Mass Flow Meter or Thermal Mass Flow Controller for accurate air flow monitoring and control
  • Tunable P-I Values Optimize DO Control
  • Five Assignable, Peristaltic Pumps built in; with control included for optional sixth pump
  • Stainless-Steel Exhaust Condenser minimizes media evaporation
  • Stainless-Steel Ring Sparger provides uniform distribution of bubbles to impeller blades
  • Battery Back-Up retains settings in the event of a power failure
 




New Brunswick BioFlo 3000

BioFlo 3000 is the gold standard laboratory scale fermenter.  It is an advanced bioprocessing system designed to maximize yields in both fermentation and cell culture. Ideally suited to meet the changing needs of the research laboratory, this versatile fermentor/bioreactor is capable of producing high yields of biomass or secreted products from virtually any microbial, animal, insect and plant cell line. The stirred-tank system comes complete with everything needed for out-of-the-box fermentor start-up, and is offered with a variety of options for dedicated cell culture applications.


Vessel Description
BioFlo 3000 is equipped with a thick-walled glass tube fermentor vessel that provides superior resistance to rough handling and repeated autoclaving. This configuration allows for significant reduction in autoclaving time compared to glass-jacketed vessels. For precise temperature control the stainless-steel base has a dished bottom that is jacketed for the circulation of warm or cool water. The BioFlo 3000 provides a closed-loop temperature control system without the need for external water baths or circulators. The vessels are interchangeable and have working volumes of 1.25, 2.5, 5.0 and 10 liters. All seals are EPDM, silicone or Teflon.

Easy handling, set-up, and installation are achieved by a detachable motor that readily couples to the agitator without tools, convenient quick-connects for jacket water circulation, and alignment pins that secure the vessel to the console without tools.
 

For a quotation reflecting your specific configuration and vessel requirements please call 763-712-8717 or complete the form on the Ordering Page.


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  GMI, Inc.
  6511 Bunker Lake Blvd.  
  Ramsey, Minnesota, 55303   USA
  Tel. 763-712-8717    Fax 763-712-8724 
 
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